Author

Mariam Jaafar

2 papers indexed here

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Open access Sep 2026

MiR-662 impairs C/D box snoRNA expression and rRNA 2′-O-ribose methylation marks

MiR-662 overexpression has been reported to promote breast cancer metastatic progression and to impair the expression of genes encoding for proteins involved in translation, ribosome biogenesis and ribosome processing (Puppo et al., 2023); however, the relationship between miR-662 and the translational machinery was no...

Charlotte Filossi, Caroline Isaac, Mariam Jaafar et al. · BJC Reports · 0 citations

Open access Aug 2026

Loss of SNORD104-guided rRNA methylation promotes early adaptation to crizotinib in lung adenocarcinoma

The ribosome, long considered an invariant actor of gene expression, recently emerged as a contributor to translational control through chemical modifications of ribosomal RNAs (rRNAs). These modifications are guided by small nucleolar RNAs (snoRNAs), which direct modifying enzymes to specific rRNA positions. Here,...

Nour-El-Houda Mourksi, Caroline Isaac, J. Ripoll et al. · Cell Death & Disease · 0 citations