Marie-Claire Blache

In vitro development of ovine follicles from the preantral to antral stages depends on initial follicle diameter and promotes oocyte growth and transzonal projections formation.

Ovine follicle culture recapitulates several features of the preantral-to-antral transition, including morphological changes and granulosa cells proliferation and differentiation. Although the influence of initial follicle diameter on in vitro development has long been suspected, it had not been investigated systematic...