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Author

Mariia Mikhova

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2 papers indexed here

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Open access Sep 2026

Tandem-Affinity Crosslinking Mass Spectrometry Supports a Model of a DNA-PKcs-PP6 Regulatory Complex.

Protein complexes can be modeled with data arising from crosslinking mass spectrometry, but it is difficult to collect such data from cellular sources, particularly for proteins that are part of extensive interaction networks. Here, we present a tandem-affinity purification crosslinking mass spectrometry (xTAP‑MS) meth...

Danny Laurent, Morgan F. Khan, Morgan Hepburn et al. · 0 citations
Open access Sep 2026

Dynamic chromatin tethering of MDC1 regulates genome stability

It is demonstrated that the proline-serine-threonine repeat region of Mediator of DNA Damage Checkpoint 1 (MDC1) is a multivalent nucleosome-binding domain, sufficient to tether chromatin in multiple contexts, and maintains genome stability during mitosis.

Joshua R. Heyza, Mariia Mikhova, Cody Phillips et al. · 0 citations

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