Open access
Jul 2026
MITD1 restricts HIV-1 release by targeting ESCRT-III proteins.
It is shown that MITD1, a cell type-specific interferon-stimulated gene, is a potent inhibitor of ESCRT-dependent HIV-1 budding, and is established as an interferon-stimulated restriction factor that limits HIV-1 egress by perturbing ESCRT-III assembly.
Jim Zoladek, Marion Cannac, Claire Lacouture et al.
· Cell Reports · 0 citations