Improving Activity and Stability of Candida boidinii Formate Dehydrogenase Through Rational Active Site Engineering
Formate dehydrogenases represent a highly attractive tool for nicotinamide cofactor regeneration to drive biocatalytic reductions and oxygenations by NADH‐dependent oxidoreductases with formate as a cheap, atom‐economic terminal reductant. However, despite the clear benefits over other recycling systems, native FDHs re...