Early-onset colorectal cancer burden attributable to early-life obesity from 2000 to 2020 with projections to 2040.
PURPOSE Early-onset colorectal cancer (age <50 years) incidence has increased globally since the 1990s for unknown reasons. Early-life exposure to established risk factors like adiposity is suspected to play a role, but the contribution to the rising disease burden remains unknown. This study quantified the potential i...