Author

Mark A. Magnuson

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Open access Aug 2026

QuantEM: An optimized platform of vision transformer-based models for segmentation and analysis of electron microscopy data

Electron microscopy (EM) is essential for resolving cellular ultrastructure, yet quantitative analysis remains limited by labor-intensive segmentation and the scarcity of generalizable models. Here we present QuantEM, an open-source platform for segmentation and analysis of EM data across imaging modalities, tissues, a...

Christopher Acree, Evan S. Krystofiak, Katie C. Coate et al. · bioRxiv · 0 citations

Open access Jul 2026

Molecular dynamics driving phenotypic divergence among KRAS mutants in pancreatic tumorigenesis.

To define mutation-specific lineage reversion and tumor initiation, Ptf1a-tdTomato mice and multiple KRAS mutants are implemented across several genetic, pharmacologic, and inflammatory perturbations in vivo to deciphering mutation-specific oncogenic trajectories and directing the implementation of KRAS-directed therap...

A. Grimont, David Falvo, W. Sisso et al. · Developmental Cell · 1 citation