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Mark Donowitz

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Open access Sep 2026

Flagellar regulation in enterotoxigenic E. coli modulates innate immune activation

ABSTRACT Enterotoxigenic Escherichia coli (ETEC) remains a leading cause of diarrheal disease in low- and middle-income countries, yet vaccine efforts have struggled to achieve broad and durable protection. To better understand early steps in host-pathogen interactions, we utilized human stem cell-derived jejunal organ...

Pauline T. Ikpa, Amanda Nengel, J. Kaper et al. · 0 citations

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