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Author

Mark E. Graham

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3 papers indexed here

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Open access Oct 2026

Identification of a Ste20-like kinase-dependent signaling network orchestrating cytoskeletal and synaptic development of cortical neurons

The Ste20-like kinase (SLK) is a serine/threonine kinase that regulates cytoskeletal organization, apoptosis, and cell polarity in non-neuronal cells. In neurons, SLK guides dendrite morphogenesis and the stability of inhibitory synapses, thereby controlling excitation-inhibition balance through parvalbumin interneuron...

Anne Quatraccioni, Mark E. Graham, M. Sylvester et al. · 0 citations
Open access Sep 2026

Phosphorylation of α-synuclein directs trafficking of the v-SNARE synaptobrevin-2.

α-Synuclein has been extensively studied for its role in Parkinson's disease, however its native function remains unclear. Several lines of evidence suggest it modulates presynaptic function. As many presynaptic proteins have their functions regulated by phosphorylation, we sought to determine whether α-synuclein, a kn...

Elyas H. Arvell, James P. Carroll, Holly Melland et al. · 0 citations

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