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Author

Mark J. Caulfield

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Open access Oct 2026

Metabolomics in Early-Phase Clinical Trials from 2010 to 2025

An international assessment of metabolomics integration in registered early-phase clinical trials provides an international assessment of metabolomics integration in registered early-phase clinical trials and concludes that metabolomics remains underutilised in early-phase clinical trials.

Jack T. Thompson, Maia Megase, M. Boffito et al. · 0 citations
Open access Sep 2026

Proteomics identify disease-associated variants in patients with rare diseases undiagnosed after genome sequencing.

It is demonstrated that serum proteomics can support rare disease diagnosis and identify disease-causing genes in patients undiagnosed after GS, although successful implementation will likely depend on tissue specificity of protein expression, detectability in blood, proteomic platform coverage, and sensitivity.

J. Carrasco-Zanini, J. Andrade, M. Pietzner et al. · 0 citations

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