Author

Markus W. Covert

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Aug 2026

Antibody Fc receptor CD16a mediates natural killer cell activation via mechanotransduction of piconewton forces

It is revealed that CD16a transduces piconewton forces and acts as a mechanosensor to facilitate NK activation, and it is demonstrated that CD16a force and the actin foci formation associated with it are essential for the phosphorylation of mechanosensitive adaptor Cas-L and signaling adaptor LAT, reshaping NK cell cyt...

Rong Ma, K. Garcia, Bian-Xiao Cui et al. · Science Advances · 0 citations

Open access Feb 2026

Antibody Fc receptor CD16a mediates natural killer cell activation via mechanotransduction of piconewton forces

Natural Killer(NK) cells eliminate target cells through antibody-dependent cell-mediated cytotoxicity(ADCC), initiated by CD16a(FcγRIIIa) recognizing the Fc region of antibodies bound to the target cell surface. While the recognition is considered to be driven by CD16a-Fc binding avidity, it fails to explain why Fc mul...

Rong Ma, K. Garcia, Bian-Xiao Cui et al. · bioRxiv · 0 citations