Marlene Jahnke

Slow Dynamics Differentially Determine the Robustness of Regular Pacemaking: Distinct Subpopulations of Midbrain Dopamine Neurons Illustrate the Principle

Pacemaking neurons, often found in mammalian nervous systems, integrate their inputs differently than quiescent neurons. Rhythmic single-spike pacemaking that is robust to noise can be achieved with a slow process that enforces a “resting potential” at each point along a ramp-like interspike interval (ISI) coupled with...