Open access
Aug 2026
Intra-host IRES heterogeneity shapes hepatitis C virus translation through epistatic and population-level effects
It is demonstrated that the full viral genome can substantially influence the activity of this regulatory region, providing a more realistic view of how translation occurs during natural infection and providing new insight into how genetic diversity drives HCV evolution and adaptation.
N. Echeverría, P. Perbolianachis, Fabiana Gámbaro et al.
· bioRxiv · 0 citations