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Martin Tomanik

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Sep 2026

Diverse Bicyclic Heterocyclic Scaffolds via Palladium-Catalyzed C(sp3)–H Activation of Amides and Amines

A carboxamide- or amine-directed Pd(II)-catalyzed tandem intramolecular β-C(sp3)–H olefination/N-cyclization has been developed for the rapid construction of [3.2.1] N-heterobicyclic frameworks, which are ubiquitous in bioactive natural products and pharmaceuticals. The transformation accommodates a range of [3.2.1]...

R. Shukla, Alpa Sharma, Bedadyuti Vedvyas Pati et al. · 0 citations

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