PGT-A, the theory versus the evidence: a systematic review on efficacy, safety, and cost-effectiveness.
BACKGROUND Preimplantation genetic testing for aneuploidy (PGT-A) aims to increase live birth rate (LBR) after IVF/ICSI. While observational studies and most systematic reviews have indicated benefits with increased LBRs and reduced miscarriage rates, results from most randomised controlled trials (RCTs) have failed to...