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Curcumin-loaded hydrogel beads were developed using hydroxypropyl distarch phosphate (HDP) and sodium alginate, including octenyl succinic anhydride (OSA)-modified alginate, for colon-directed delivery and anticancer evaluation against Caco-2 cells. Alginate was modified with 1%, 2%, and 3% OSA, yielding degrees of sub...
Combining pooled cancer-associated network pharmacology with co-crystallized ligand benchmarking suggests that CBD may exert its biological activity through coordinated modulation of multiple cancer-related signaling pathways rather than a single molecular target.
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