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Author

Mason R. Arbery

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Open access Sep 2026

BAG3 coordinates astrocytic proteostasis of Alzheimer's disease-linked proteins via proteasome, autophagy, and retromer interactions.

Bcl-2-associated athanogene 3 (BAG3) is a mediator of chaperone-assisted selective autophagy, and in the brain, is most highly expressed in astrocytes. However, its role in astrocytes remains poorly defined. Given the genetic and pathological links of BAG3 to proteostasis and neurodegenerative diseases, we investigated...

Zachary M. Augur, Garrett M. Fogo, Courtney R. Benoit et al. · 0 citations
Open access Sep 2026

Decentralizing Clinical Tumor Exome Analysis: On-Premises GPU-Based Secondary Analysis in a Clinical Molecular Laboratory

Background/Objectives: Clinical tumor sequencing has become central to precision oncology, yet secondary genomic analysis remains heavily dependent on cloud or centralized computational infrastructure, creating barriers related to cost, turnaround time, data governance, and accessibility. We demonstrate that secondary...

P. Ahluwalia, Denton Lord, Mason R. Arbery et al. · 0 citations

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