Aug 2026
Design, Synthesis, and Antitumor Activity Evaluation of Novel Dual A2A/A2B Adenosine Receptor Antagonists.
Adenosine is an essential signaling molecule with a well-recognized role in the central nervous, cardiovascular, and immune systems. Its immunosuppressive effects have gained significant attention in oncology, as adenosine accumulation within the tumor microenvironment can profoundly inhibit antitumor immunity. Therape...
M. Gałęzowski, M. Kujawa, A. Bobowska et al.
· Journal of Medicinal Chemist... · 0 citations