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Author

Matilde Costa

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Open access Oct 2026

Integrated Two-Step Membrane Chromatography for Robust and High-Throughput Plasmid DNA Purification

Plasmid DNA (pDNA) is a key raw material for advanced therapeutic modalities, including gene therapy, mRNA production, and DNA vaccination, requiring efficient and scalable downstream processing strategies. Increasing demand places stringent requirements on purification processes in terms of yield, impurity removal, pr...

Matilde Costa, S. Cardoso, I. Marçal et al. · 0 citations

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