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Matthew A. Rangel

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Open access Sep 2026

Snapshots from the Catalytic Landscape of Chalcone Isomerase

Chalcone isomerase (CHI) catalyzes the cyclization of 3-ring scaffolds of flavonoids, a class of plant-based natural products important for nutrition and disease prevention. A persistent question has been whether the enzyme uses dynamics to facilitate conformational rearrangements of substrates within the active site....

J. Burke, Matthew A. Rangel, Vanessa I. Vasquez Meza et al. · 0 citations

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