Author

Matthew D. Mann

h-index 2 View on Semantic Scholar

We have 2 of 7 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Jul 2026

Discovery of low molecular weight protein-binding fragments from bead-displayed libraries: application to monomeric proteins

Various strategies to multimerize monomeric targets are explored, thus allowing them to be used as targets in this fragment discovery platform and a particularly effective and convenient strategy is to express a fusion of the POI with FOLDON, a 30-residue, homo-trimeric peptide.

Joel Tong, Isuru M. Jayalath, James V. Parsons et al. · RSC Chemical Biology · 0 citations

Open access Jul 2026

Rational design of RORγT small molecule modulators results in tunable LXRα pleiotropic effects in Th17 cells 2267479

Rational design of small molecule modulators enhanced RORγT inverse agonism and tuned LXRα agonism enhanced RORγT inverse agonism and tuned LXRα agonism better suppressed the pathogenic Th17 phenotype, reducing IL-17 secretion and downstream gene expression.

Matthew D. Mann, Mi-Ra Chang, Vuong Q. Dang et al. · Journal of Immunology · 0 citations