Author

Matthew E. Larkum

3 papers indexed here

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Open access Oct 2026

Memory-based and surround-based pattern completion show distinct laminar profiles in human V1

Visual input is often incomplete, requiring the brain to infer missing information from prior experience or contextual cues. Establishing whether memory-derived and context-derived information shape pattern completion through shared or distinct top-down pathways is central to understanding how perception emerges from t...

Zi-Rui Zhang, Clement Abbatecola, Ying-Ying Huang et al. · bioRxiv · 0 citations

Open access Sep 2026

Dendritic hotspots support switching between competing rules without expanding the cortical engram

Adaptive behavior requires updating responses when contingencies change while preserving prior associations and the capacity to learn a new. How this trade-off is resolved remains unknown. Here, we combined in vivo imaging of apical tuft spines in the secondary motor cortex (M2) with biologically constrained network mo...

I. Pandi, Spyridon Chavlis, Hatem Oraby et al. · bioRxiv · 0 citations

#artificial intelligence Preprint Sep 2026

Programs-of-Layers in LLMs through the Lens of Cortical Areas

Inference in LLMs is conventionally a fixed-depth, fixed-order forward pass through every layer, regardless of how difficult the input is. The human brain does not work this way: using the thalamus as a central hub, it routes information flexibly to all regions of the cortex according to demand. Li et al. (2026) recent...

Justus Westerhoff, Stephan Olbrich, Hatem Oraby et al. · 1 citation