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Matthieu Lepage

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Open access Aug 2026

TMPRSS6 Cleavage of β-Klotho Modulates FGF19 Signaling

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent liver disorder worldwide, yet therapeutic options remain limited. TMPRSS6, a liver serine protease best known for its role in iron homeostasis, has recently emerged as a potential therapeutic target for MASLD. However, the molecular...

Matthieu Lepage, A. Désilets, Gabriel Lemieux et al. · 0 citations

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