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Author

Md. Abul Hassan Samee

2 papers indexed here

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Open access Jul 2026

Kernelized approach enables explainable gene prioritizations for complex traits

Genome-wide association studies (GWAS) have identified numerous variant-trait associations; yet, assigning effector genes to GWAS loci remains challenging. Similarity-based machine-learning methods, such as PoPS, prioritize effector genes from shared functional profiles among trait-relevant genes. These models assign a...

Taotao Tan, Md. Abul Hassan Samee · 0 citations
Open access Jul 2026

SPARC: A Graph-based Optimization Framework for Directional Trajectory Reconstruction Across Ordered Single-Cell Conditions

Single-cell transcriptomics has enabled systematic profiling of cellular states across ordered biological contexts, including developmental stages, treatment phases, disease progression, and anatomical compartments. A central challenge is to reconstruct trajectories that respect the directionality imposed by biology or...

Shifeng Wu, W. C. Walker, Carolyn A. Martin et al. · 0 citations

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