Recent Progress in Chitosan Nanoparticles for the Oral Delivery of Proteins and Peptides: Strategies to Improve Bioavailability.
INTRODUCTION The oral delivery of proteins or peptides remains a significant challenge due to enzymatic degradation in the gastrointestinal tract, low epithelial permeability, and low bioavailability. Chitosan nanoparticles (CNPs) have been developed to overcome these disadvantages due to their biodegradability, biocom...