Hydroxyurea-Loaded Nanostructured Lipid Carriers for Enhanced In Vitro Cytotoxicity and Drug Delivery.
Hydroxyurea (HU) is an established anticancer drug used to treat chronic myelogenous leukemia, but its therapeutic efficacy is limited by rapid clearance, variable bioavailability, and dose-related toxicity. This study aimed to improve HU delivery by developing hydroxyurea-loaded nanostructured lipid carriers (NLCs) us...