Mirtron Overexpression Drives Immune Modulation and Tumor Progression Through Macrophage Polarization and Oncogenic Pathway Regulation 2309835
Mirtrons, a specialized subclass of intron-derived microRNAs (miRNAs), bypass canonical Drosha-dependent processing by undergoing splicing and debranching to form pre-miRNA hairpins directly processed by Dicer. This alternative pathway imparts high structural stability and resistance to exonucleolytic degradation...