Meghan E. McGee-Lawrence

Defining the potential role of the mineralocorticoid receptor in musculoskeletal health and bone crosstalk with other tissues

Excessive mineralocorticoid receptor (MR) activation in the heart and vasculature leads to pathological effects such as extracellular matrix accumulation, oxidative stress, and sustained inflammation. While MR’s role in cardiovascular and renal systems is well understood, MR signaling has also been implicated as a key...