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It is suggested that pyrethroid exposure, particularly fenvalerate, may contribute to dyslipidemia and highlight the need for further mechanistic investigation and risk evaluation.
It is suggested that vitamin D metabolites may have distinct associations with incident CVD among individuals with T2D, highlighting the importance of distinguishing individual vitamin D metabolites in CVD risk assessment.
Despite ubiquity of contaminants of emerging concern (CECs), biological consequences of combined exposure remain poorly understood, particularly regarding oxidative stress and related redox-sensitive molecular responses. We quantified 64 urinary CECs across seven chemical classes (bisphenol analogues, parabens, synth...
The observed effect modification by CYP19A1 rs2414098 suggests that hormonal pathways may contribute to the sex-specific associations, although this hypothesis requires confirmation in studies with direct hormone measurements and experimental validation.
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