Mei-Hui Zhang

Discovery and optimization of A 2-phenyl-1,2,4-triazolidin-3-one scaffold as potent ferroptosis inhibitors for hepatoprotection.

Ferroptosis is a regulated form of cell death that plays a critical role in the initiation and progression of various liver diseases. Identifying novel ferroptosis inhibitors may therefore offer promising therapeutic benefits for ferroptosis-related liver diseases. Through screening of a small-molecule compound library...