Review
Open access
Sep 2026
Lung Cancer Brain Metastasis: Brain Microenvironmental Adaptation, Therapeutic Resistance and Translational Strategies
ABSTRACT Lung cancer brain metastasis (LCBM) remains one of the most challenging clinical conditions limiting survival and neurological function. The development of LCBM is shaped by continuous exchange of molecular signals between tumor cells and the brain microenvironment, involving blood–brain barrier remodeling, gl...
Jun Yang, Jun-Yi Xiong, Li Ying et al.
· Cancer Science · 0 citations