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Mei-Na Cai

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Open access Sep 2026

Consensus H3N2 HA immunogens incorporating key antigenic mutations elicit broad-spectrum neutralizing responses

ABSTRACT Seasonal influenza A/H3N2 poses a significant public health burden due to its rapid antigenic evolution, necessitating frequent vaccine updates. This study systematically analysed the antigenic evolution of 14 H3N2 vaccine strains (2000–2022) using pseudovirus-based neutralization assays and antigenic cartogra...

Yi-Meng An, Mei-Na Cai, Chen-Yan Zhao et al. · 0 citations

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