Mei-Xuan Li

Beyond the glomerular filtration barrier: How endothelial glycocalyx damage drives kidney disease in diabetes.

Current therapies for diabetic kidney disease (DKD) slow progression but fail to halt irreversible renal fibrosis, largely because early pathogenic drivers are overlooked. While endothelial glycocalyx disruption is recognized as an initiator of albuminuria, existing literature lacks a unified model connecting this init...