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Author

Meike Schopp

2 papers indexed here

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Oct 2026

Meso-scale spatial analysis of papilloma formation and clonal expansion in cancerized skin.

Somatic driver mutations pervade phenotypically normal epithelia, yet only a minority of clones progress to tumors. To understand how tissue context modulates clonal selection, we apply the classical two-stage DMBA/TPA model of carcinogenesis to mouse back skin. We collect coordinate-registered, meso-scale grids spanni...

V. Busa, Mikaela Behm, Pablo Baeza-Centurión et al. · 0 citations
Open access Jul 2026

Cumulative transcription factor binding and p300-mediated histone acetylation drive enhancer activation frequency

The data support a model in which enhancer activation frequency depends on the cumulative function of multiple TFs and is modulated by p300 activity, and the contributions of transcription factor binding and chromatin context are dissected.

Valentina Baderna, Guido Barzaghi, Rozemarijn Kleinendorst et al. · 3 citations

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