Open access
Jul 2026
TTYH3 regulates a lysosomal chloride conductance and controls lysosomal fusion, autophagy and senescence.
It is demonstrated that TTYH3 mediates a lysosomal chloride conductance and regulates lysosomal physiology and autophagy, and may serve as a potential therapeutic target for interventions in aging and lysosome-related diseases.
Jiamin Huang, Ya-Yu Wang, Yu-Dong Xu et al.
· Cell Reports · 0 citations