Evaluating the impact of methodological trade-offs on meta-analyses and certainty of the evidence according to GRADE: Part 5 of a meta-research study of rapid reviews.
OBJECTIVE To determine whether methodological trade-offs used in rapid reviews result in changes in treatment effects or GRADE certainty of the evidence (COE) compared to systematic reviews. DESIGN AND SETTING We used three systematic reviews on acupuncture, education, and TENS for the management of chronic low back...