BACKGROUND
Narcolepsy type 1 is characterized by excessive daytime sleepiness, cataplexy, disrupted sleep, sleep paralysis, and hypnagogic or hypnopompic hallucinations. Oveporexton (TAK-861), an oral orexin receptor 2-selective agonist, reduced symptoms of narcolepsy type 1 in a previous phase 2 trial.
METHODS
We co...
Y. Dauvilliers, Emmanuel Mignot, Jakub Antczak et al.· New England Journal of Medic...· 1 citation
STUDY OBJECTIVES
Excessive daytime sleepiness is a defining symptom of narcolepsy, affecting daily functioning and quality of life. We developed and evaluated an actigraphy-based nap detection algorithm to objectively estimate daytime naps, a key manifestation of excessive daytime sleepiness.
METHODS
The nap detectio...
R. Torres, Rahul Ghosal, Melissa Naylor et al.· Sleep· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.