Mass Spectrometry-Based Multiomic Profiling Defines Proteome, Lipidome, and Metabolome Remodeling in IFN-γ and LPS-Stimulated BV-2 Microglial Cells
Microglial inflammatory activation is accompanied by extensive molecular remodeling, yet proteomic, lipidomic, and metabolomic responses are often analyzed independently. Here, we applied an integrated mass spectrometry-based multiomic workflow to characterize proteomic, lipidomic, and polar metabolomic remodeling from...