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Review Open access Aug 2026

Cholinergic dysfunction in Alzheimer's disease: Mechanistic perspectives and multi-target effects of traditional Chinese medicine.

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by progressive cognitive decline and complex pathological changes. Cholinergic dysfunction is an early, clinically pivotal feature of AD closely associated with multiple pathological processes, including amyloid-β (Aβ) pathology, neur...

Yi-Xin Wang, Hong-Xing Li, Lingfang Hao et al. · 0 citations
Review Sep 2026

Lipid regulation of mitochondrial function in metabolic Diseases: Lipotoxic mediators and therapeutic targeting.

Lipid dysregulation is a key driver of chronic metabolic and degenerative diseases. However, lipid abnormalities and mitochondrial dysfunction are often examined separately, with limited attention given to their mechanistic links. As the central hub of energy metabolism, mitochondria continuously adapt their structure,...

Hao Cui, Hong-Xing Li, Wei-Hua Wang et al. · 0 citations

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