Meng-Dan Xu

Active Lysosomal Nanoplatform for Ferroptosis-Enhanced Immunotherapy via Tumor Extracellular Matrix Remodeling.

The therapeutic efficacy of nanomedicines in solid tumors is often limited by rapid systemic clearance, dense extracellular matrix (ECM) barriers, poor tumor cell selectivity, and an immunosuppressive tumor microenvironment. Herein, we report an active lysosome-encapsulated hollow mesoporous Prussian blue nanoparticle...