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Review Open access Sep 2026

Aptamer-Based Heterobifunctional Targeted Degraders in Disease Treatment

Aptamers are short nucleic acid molecules that bind to targets with high specificity. Recognized as “chemical antibodies”, they offer distinct advantages including strong programmability and ease of synthesis and chemical modification. Heterobifunctional targeted degraders were developed to address the challenges posed...

Xiuhua Liang, Meng Du, Jing Wang et al. · 0 citations

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