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Author

Meng-Fei Yu

2 papers indexed here

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Aug 2026

Engineering Biomimetic Tumor Organoids Inspired by Janus Stiffness-Driven Cell Stemness.

Organoids become powerful platforms for modeling cancer biology but poorly preserve stemness due to inadequate biophysical cues. Cancer stem cells (CSCs), crucial for tumor growth, are rare and lose stemness under conventional in vitro conditions, limiting drug screening. While chemical and genetic stemness regulators...

Zi-Yu Zhu, Siyi Zhou, Tianyi Gu et al. · 0 citations
Open access Aug 2026

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

ABSTRACT Repairing peripheral nerve injury remains a clinical challenge due to its limited regenerative capacity and the situation is further compounded with age. In this study, we identified the dysregulated repair program of Schwann cells (SCs) as a key feature of the aging‐dependent impairment of nerve regeneration,...

Ning Zhan, Lixin Tian, Lian-Jie Peng et al. · 0 citations

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