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Meng-Han Wu

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Open access Oct 2026

Macrophage-induced ferritin expression protects pancreatic cancer cells from ferroptosis.

Reactive oxygen species (ROS) drive pro-tumorigenic signaling but also promote lipid peroxidation and ferroptosis, making ROS regulation critical during high oxidative stress stages of tumor progression, such as metastasis. Loss of the antioxidant TIGAR in pancreatic ductal adenocarcinoma (PDAC) cells raises ROS and en...

Eric C. Cheung, Meng-Han Wu, Wen-Chih Cheng et al. · 0 citations

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