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Meng-Huai Wu

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Open access Aug 2026

CD44v6- and VEGFR2-targeting antibody-drug conjugates: Enhancing precision and safety in cancer therapy through a dual-targeting strategy.

BACKGROUND Bispecific antibody-drug conjugates (BsADCs) represent a promising therapeutic strategy to overcome single-target resistance. Here, we developed a dual-targeting BsADC that simultaneously recognizes CD44v6 and VEGFR2. METHODS Spatial configurations were optimized in CHO expression systems. In vitro binding...

Meng-Huai Wu, Xuezhe Feng, Wen-Qian Huang et al. · 0 citations

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