Resveratrol attenuates LPS/CSE-induced macrophage ferroptosis through activation of the Nrf2-ferroportin axis.
BACKGROUND Resveratrol (Res) has therapeutic effects in a mouse model with chronic obstructive pulmonary disease (COPD). However, the role of ferroportin (FPN) in the Res-mediated therapeutic effects remains unclear. PURPOSE We investigated the role and signaling pathways of FPN in macrophages and a mouse model with...