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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Meng-Jie Zhang

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Open access Sep 2026

Histone lactylation regulates macrophage polarization and metabolic homeostasis during hypoxic lung injury.

The M1-to-M2 macrophage phenotypic switch is critical for resolving inflammation and restoring homeostasis in hypoxic lung injury, but the underlying molecular mechanisms are unclear. Here, we show that hypoxia-induced histone lactylation (Kla) upregulates FTO via HIF1a-P300 interaction; lactylation-driven FTO then pro...

Xing-Wang Zhao, Meng-Jie Zhang, Jun Yin et al. · 0 citations

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