Open access
Sep 2026
Emodin alleviates endometrial fibrosis via METTL3/YTHDF2-mediated m6A modification of PPARα and the fatty acid oxidation pathway
This study aimed to investigate the anti-fibrotic mechanism of emodin in endometrial stromal cells (ESCs), focusing on the N6-methyladenosine (m6A) modification of PPARα. An in vitro fibrosis model was established by treating ESCs with TGF-β1. Emodin was then administered to the cells, and its effects on fibrosis, ce...
Zhi-Tao Yao, Da-Bao Xu, Qiu Lin et al.
· Scientific Reports · 0 citations