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Author

Meng-Lin Cao

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Open access Oct 2026

Dual-Functional Cu-Engineered CFR-PEEK Interfaces Combat Infection and Orchestrate Vascularized Bone Regeneration via Osteoimmunomodulation

Constructing a bioactive interface on bio-inert polyetheretherketone (PEEK) to concurrently counteract bacterial infection and orchestrate favorable osteoimmunomodulation remains a formidable challenge. Here, we engineer a hierarchical micro/nano-topography on carbon fiber-reinforced PEEK (CFR-PEEK) via acid etching,...

Jing-Jing Su, Meng-Lin Cao, Yuxuan Lin et al. · 0 citations
Open access Sep 2026

Dopamine-Functionalized Osteon-Mimetic Polycaprolactone/β-Tricalcium phosphate Membranes: Antibacterial Efficacy and MAPK/p53-Mediated Osteohomeostasis

In vivo evaluations in a rat calvarial defect model demonstrated that 24DOPA@M-PCL/β-TCP facilitated superior bone regeneration, characterized by elevated osteocalcin/osteopontin expression and reduced TRAP-positive osteoclast recruitment, underscore the significant clinical translational potential of this biomimetic,...

Yi-Xuan Lei, Jing-Jing Su, Wei-Xin Wang et al. · 0 citations

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