Author

Meng-Meng Zheng

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Open access Sep 2026

Structural and Mechanistic Basis of Dual Substrate Promiscuity in the Acyltransferase AntB Enables Late-Stage Diversification of Natural Products.

Biocatalytic regioselective acylation is a powerful strategy for diversifying natural products and optimizing their pharmacological properties. Compared with plant acyltransferases (ATs), bacterial tailoring ATs remain poorly understood. AntB from the antimycin pathway was previously reported to possess acyl-donor prom...

Meng-Meng Zheng, Yu-Han Dai, Xiang-Yu Li et al. · Angewandte Chemie · 0 citations

Open access Aug 2026

Comparative Transcriptomic Analysis Provides Insights into PSK-α-Mediated Regulation of Diosgenin Biosynthesis in Trigonella foenum-graecum

Diosgenin is an important steroidal sapogenin widely used for the industrial production of steroidal drugs. Phytosulfokine-α (PSK-α) is a sulfated pentapeptide hormone known to regulate plant growth, development, and stress responses. However, its role in the regulation of diosgenin biosynthesis remains unclear. Fenugr...

Chuanjia Xu, Hao Zhan, Malakkhanim Mehraliyeva et al. · Molecules · 0 citations