Thrombus-Targeted and Reactive Oxygen Species-Responsive Apigenin Liposomes for Ischemic Stroke.
Ischemic stroke remains a leading cause of mortality and long-term disability, while current therapies inadequately address oxidative stress, mitochondrial dysfunction, and blood-brain barrier (BBB) disruption during ischemia and reperfusion. Here, we developed DPCT@LIP-AP, a reactive oxygen species (ROS) responsive li...